The Role of PGD and PGS Test in Best IVF Center Hyderabad : What You Need to Know
In vitro fertilisation (IVF) is a medical procedure that gives hope to millions of couples struggling to conceive. In recent years, the success rate of IVF has significantly increased, thanks to advancements in medical technology. However, IVF success is not guaranteed,
and one of the major factors that determine the success rate is the quality of embryos used for implantation. This is where PGD and PGS testing comes in for Felicity, the best IVF centre in Hyderabad.
Introduction to IVF and its success rate
IVF is a procedure where eggs are retrieved from a woman’s ovaries and fertilised with sperm in a laboratory. The resulting embryos are then transferred to the woman’s uterus, where they can implant and grow into a healthy baby. IVF is a complex procedure that requires expertise and state-of-the-art facilities. The success rate of IVF varies depending on several factors, including the age of the woman, the quality of the eggs and sperm, and the experience of the IVF centre.
In general, the success rate of IVF has been increasing over the years. However, the success rate can vary significantly depending on the individual’s circumstances.
What is PGD testing?
Preimplantation genetic diagnosis (PGD) is a technique used to screen embryos for genetic abnormalities before implantation. PGD IVF testing is performed on embryos that have been created through IVF. The procedure involves removing one or more cells from the embryo and analysing them for genetic abnormalities.
PGD testing can be used to detect chromosomal abnormalities, such as Down syndrome, and genetic disorders, such as cystic fibrosis. This kind of testing can also be used to determine the sex of the embryo, which is helpful in cases where gender-linked genetic disorders are a concern.
What is PGS testing?
Preimplantation genetic screening (PGS) is a similar technique to PGD testing, but it is used to screen embryos for chromosomal abnormalities only. PGS IVF testing involves analysing the chromosomal makeup of the embryo to ensure that it has the correct number of chromosomes. Having an abnormal number of chromosomes can lead to miscarriage or birth defects.
PGS testing is especially helpful for older women who are at a higher risk of having embryos with chromosomal abnormalities. It can also be used to screen embryos for specific genetic disorders if the parents are carriers of a genetic disorder.
Benefits of PGD and PGS testing
The benefits of PGD and PGS testing in Felicity, the best IVF center in Hyderabad are numerous. Here are the top 5 benefits:
Early Detection of Genetic Disorders
PGD and PGS testing can identify genetic abnormalities in embryos before implantation, allowing prospective parents to make informed decisions regarding their reproductive choices. This early detection helps prevent the transfer of embryos with genetic disorders, reducing the risk of passing on genetic conditions to future generations.
Increased Chance of Successful Pregnancy
By screening embryos for genetic abnormalities, PGD and PGS testing can improve the success rates of assisted reproductive technologies such as in vitro fertilization (IVF). Only healthy embryos are selected for transfer, increasing the likelihood of achieving a successful pregnancy and live birth.
Reduced Risk of Pregnancy Loss
Identifying genetically abnormal embryos through PGD and PGS testing helps reduce the risk of miscarriages and pregnancy losses. By selecting embryos with the correct number of chromosomes, the chances of implantation and healthy fetal development are significantly improved.
Enhanced Family Planning
PGD and PGS testing provides valuable information about an embryo’s genetic status, allowing prospective parents to make informed decisions regarding family planning. This information can help individuals or couples who have a higher risk of transmitting certain genetic disorders to decide on the most suitable reproductive options, such as selecting embryos without the specific genetic condition.
Peace of Mind
PGD and PGS testing offers peace of mind to prospective parents by providing them with valuable insights into the genetic health of their embryos. By screening for genetic abnormalities, these tests can alleviate anxiety and uncertainty associated with the risk of passing on inherited genetic disorders, empowering individuals or couples to make more informed choices about their reproductive journey.
PGD and PGS testing process
Consultation
The prospective parents meet with a genetic counsellor or fertility specialist to discuss their medical history, family history of genetic disorders, and their reasons for pursuing PGD or PGS testing. They also learn about the testing process, its benefits, and any potential risks or limitations.
In Vitro Fertilisation (IVF)
PGD and PGS testing is performed in conjunction with IVF. The woman undergoes ovarian stimulation to produce multiple eggs, which are then retrieved for fertilisation with the partner’s or donor’s sperm in a laboratory setting.
Embryo Development
The fertilised eggs, now called embryos, are cultured in a laboratory for a few days until they reach the blastocyst stage, typically around day 5 or 6 after fertilization. During this time, the embryos continue to divide and develop.
Biopsy
A small number of cells are carefully removed from each viable embryo. The biopsy can be performed using different techniques, such as removing a few cells from the outer layer (trophectoderm) of the blastocyst for PGS testing or removing one or two cells from the embryo for PGD testing.
Genetic Analysis
The biopsied cells are sent to a genetic laboratory where they undergo genetic analysis. The specific testing method may vary depending on the desired outcome, such as analysing the chromosomes for PGS or targeting specific genetic mutations for PGD.
Embryo Selection
The results of the genetic analysis are provided to the reproductive specialist and prospective parents. Based on the genetic information, the most viable and genetically healthy embryos are selected for transfer to the woman’s uterus. The remaining embryos may be cryopreserved (frozen) for future use.
Embryo Transfer
The selected embryos are transferred into the woman’s uterus using a thin catheter. This procedure is typically performed a few days after the biopsy, depending on the stage of embryo development.
Pregnancy Test and Follow-up
Approximately two weeks after the embryo transfer, a pregnancy test is conducted to determine if implantation and pregnancy have occurred. If pregnancy is achieved, the woman receives ongoing prenatal care and monitoring to ensure a healthy pregnancy.
It’s important to note that the specific steps and techniques used in PGD and PGS testing may vary among clinics and individual cases, and the process may be adjusted based on the unique circumstances and preferences of the prospective parents.
Frequently asked questions about PGD and PGS testing
Is PGD testing safe for the embryo?
Yes, PGD IVF testing is safe for the embryo. The biopsy only removes one or a few cells from the embryo, which does not harm the embryo’s development.
What is the success rate of IVF with PGD and PGS testing?
The success rate of IVF with PGD and PGS testing varies depending on the individual’s circumstances. However, studies have shown that using PGD and PGS testing can increase the success rate of IVF.
Is PGD and PGS testing covered by insurance?
Some insurance plans cover PGD and PGS IVF testing, but it is important to check with your insurance provider to confirm coverage.
Consult the experts at Felicity IVF & Fertility Center today to learn more about how PGD and PGS testing can help you achieve your dream of parenthood.
